Biotinoyl Tripeptide-1Biotinyl-GHK
Biotinoyl Tripeptide-1 is an active biotinylated peptide for hair care formulations. It targets the follicle area to support hair root structure and maintain scalp barrier health. Xi'an Wanlu supplies cosmetic-grade Biotinoyl Tripeptide-1. Please confirm quantity before purchase; relevant documentation is available.
Overview
What is Biotinoyl Tripeptide-1?Biotinoyl Tripeptide-1 (abbreviated as Bio-GHK) is a cosmetic active peptide formed by covalent bonding of biotin and GHK tripeptide. It is the core active monomer used in the Procapil formulation system. This raw material is readily soluble in water. In vitro studies indicate that it can act on the basement membrane of hair follicles, help support the expression of type IV collagen and laminin‑5, maintain stable hair root structure and reduce the probability of hair breakage. Meanwhile, the biotin moiety participates in keratin synthesis, providing nutritional support for hair follicles, helping optimize the condition of fine and soft hair, and improving the fluffy texture of hair. It can also be applied to eyelash and eyebrow care. Recommended for leave‑on products such as scalp serums and eyelash nourishing liquids. Add at low temperature in the aqueous phase, compatible with pH 4.5–7.0 systems, and features good stability.
Key Parameters
Applications
Scalp & Hair Care Products
1. Product forms: Leave-on regular hair care products such as scalp serums and scalp lotions. 2. Application principle: In vitro studies show it helps support the expression of collagen and laminin, maintain hair root structure, care for the scalp and follicle environment, and optimize hair condition. It can be used as an active ingredient in scalp care formulations.
Daily Wash-off Hair Care Products
1. Product forms: Shampoos, hair conditioners, hair masks, hair cleansing creams, etc. 2. Application principle: Can be incorporated into daily wash-off formulations to help condition the scalp environment, improve hair texture and impart good luster to hair. Note: The residence time of active ingredients in wash-off products is limited; comprehensive consideration is required during formulation design.
Eyebrow & Eyelash Care Products
1. Product forms: Leave-on care products such as eyelash serums and eyebrow care essences. 2. Application principle: In vitro studies show it can participate in keratin synthesis, condition the follicle environment and help improve the state of eyebrow and eyelash hairs.
Product FAQ
What are the INCI name and CAS number of Biotinoyl Tripeptide-1?
INCI Name: Biotinoyl Tripeptide-1; Chinese Name: 生物素三肽 - 1; CAS No.: 299157-54-3, cosmetic-grade peptide raw material.
What are the appearance and solubility properties of Biotinoyl Tripeptide-1?
It appears as white to off-white fine powder. It is a water-soluble peptide, readily soluble in aqueous phase and insoluble in oil systems, suitable for addition in water-phase formulations.
What cosmetic formulations can Biotinoyl Tripeptide-1 be applied to?
It can be used in leave-on products such as scalp care serums, scalp lotions, eyelash care liquids and eyebrow care essences. It can also be added into wash-off formulations including shampoos, hair conditioners and hair masks. In vitro literature studies indicate it can act as an active ingredient in hair care formulations.
What are the standard packaging specifications of Biotinoyl Tripeptide-1?
Standard sealed packages: 1g, 10g, 100g. Custom packaging available; independent vials for samples.
What raw materials are commonly formulated together with Biotinoyl Tripeptide-1?
Frequently combined with water-soluble peptides, moisturizing and soothing ingredients for formulation R&D reference. 1. Acetyl Hexapeptide-8: co-formulated peptide within the same system, widely used in leave-on scalp, eyebrow and eyelash care formulations. 2. Sodium Hyaluronate (low / medium molecular weight): moisturizing base, improves formulation sensory feel and maintains scalp hydration. 3. Panthenol (Vitamin B5): moisturizing & soothing, suitable for scalp care serums. 4. Copper Tripeptide-1 (GHK-Cu): peptide blend for premium scalp care formulations; stability test is required before compounding. 5. Biotin (Vitamin H): homologous active component, classic combination for hair care formulations. 6. Dipotassium Glycyrrhizate: soothing ingredient, ideal for sensitive scalp formulations. Note: Pre-formulation compatibility and stability tests are recommended for all blended formulas to confirm system compatibility before mass production.