Recombinant Humanized Type I CollagenCollagen I
Recombinant Humanized Type I Collagen is a water-soluble raw material for repair and conditioning. Please confirm application purpose, grade, content and required quantity before inquiry. Xi'an Wanlv can match relevant documents and products.
Overview
What is Recombinant Humanized Type I Collagen?Recombinant Humanized Type I Collagen is a class of collagen produced by synthetic biology technologies combining genetic engineering and microbial fermentation. Through gene design, the target gene encoding human type I collagen is introduced into engineered microorganisms to construct microbial cell factories. The target protein is obtained via fermentation, expression, separation and purification. Type I collagen is the primary structural collagen in human dermis. The amino acid sequence of this product is designed based on human type I collagen and shares high sequence homology with native human type I collagen. Unlike collagen extracted from animal tissues, it is produced entirely from non-animal sources without introducing animal-derived components, reducing potential risks of zoonotic viruses and sensitization caused by heterologous proteins. Normally supplied as water-soluble lyophilized powder, it contains functional cell-recognition sites such as RGD. It can be used as raw material in cosmetics, medical dressings, tissue repair materials and other fields.
Key Parameters
Applications
Cosmetics & Personal Care
1. Applied in skincare formulations such as serums, facial masks, single-dose ampoules, creams and sprays. 2. Suitable for the development of moisturizing formulations. The raw material has structural properties to form protein matrices.
Medical Device Raw Material
1. Raw material for collagen dressings, hydrogels, collagen membranes and lyophilized sponges. Finished products shall complete medical device registration in accordance with regulations. 2. Raw material for collagen lyophilized fibers and soft tissue matrix R&D. If used for implantable devices, finished products require separate medical device registration. 3. R&D raw material for oral mucosal matrix, soft tissue scaffolds and tissue engineering scaffolds.
Research & Cell Culture
1. Cell culture coating substrate for cell adhesion and construction of in vitro cell models. 2. Basic research for tissue engineering and biomaterials.
Product FAQ
What is Recombinant Humanized Type I Collagen?
Recombinant Humanized Type I Collagen is produced by genetic engineering and synthetic biology technology via fermentation and expression in microbial cell factories. Its amino acid sequence is designed based on human Type I collagen and shares high sequence homology with native human Type I collagen. Manufactured without animal sources, it differs from collagen extracted from animal tissues and reduces potential risks associated with animal-derived viruses and heterologous proteins. Supplied as water-soluble lyophilized powder containing RGD cell-recognition sites, it can be used as raw material for cosmetics, medical dressings, research cell culture and other applications.
What is the recommended dosage of Recombinant Humanized Type I Collagen in cosmetics?
The recommended dosage range for cosmetic formulations is 0.01%–0.5%. Low-temperature feeding below 40°C is suggested; the formula pH should be controlled between 4.0–7.0. Avoid high temperature, strong acid and strong alkaline environments to prevent protein denaturation. The dosage for medical dressing formulations can be customized according to product plans.
What are the differences between Recombinant Humanized Type I Collagen and animal-extracted collagen?
This product is produced by microbial fermentation and contains no animal-derived components, which can avoid potential risks of animal-borne viruses and heterologous proteins. It features controllable batch consistency and high protein purity. Collagen extracted from animal tissues has inherent drawbacks such as heterologous proteins and batch-to-batch variation due to raw material sourcing characteristics.
What are the storage conditions and packaging specifications of Recombinant Humanized Type I Collagen?
Seal and protect from light, store under refrigeration at 2～8°C. Standard packaging specifications: 10g/bottle, 100g/bottle, 1kg/bottle. Small-batch aliquoting service available. Cold-chain transportation is recommended; avoid prolonged exposure at ambient temperature.