Palmitoyl Tetrapeptide-10
Palmitoyl Tetrapeptide-10 is a lipophilic signal cosmetic peptide. It improves the penetration and retention of raw material on the skin surface, helps maintain skin barrier homeostasis, assists in improving rough skin texture, and supports smooth and firm skin appearance. It is compatible with various skincare formulations, featuring stable quality. Samples are available for testing.
Overview
What is Palmitoyl Tetrapeptide-10?Palmitoyl Tetrapeptide-10 (INCI: Palmitoyl Tetrapeptide-10, CAS: 887140-79-6) is a synthetic lipophilic signal cosmetic peptide listed in the China Inventory of Existing Cosmetic Ingredients. It is covalently formed by palmitic acid and a tetrapeptide fragment. The long palmitoyl chain improves molecular skin affinity and skin surface retention capacity. This raw material acts on the dermal-epidermal junction (DEJ). It can regulate the expression of relevant structural proteins in this region, maintain the homeostasis of the dermal-epidermal junction, and support skin barrier homeostasis. It helps soothe skin discomfort caused by external stimuli, assists in improving the visual appearance of rough skin texture, and helps maintain a smooth and firm skin appearance. It appears as white to off-white powder. The recommended dosage ranges from 0.001% to 0.05%. It is suitable for emulsified skincare systems such as serums, lotions and creams within pH 4.0–7.0. It can be compounded with a variety of active raw materials, featuring stable batch quality. COA and MSDS are available, and samples can be provided for evaluation.
Key Parameters
Applications
Facial Skincare
1. Radiance Texturizing Serum / Polishing Serum: Helps achieve translucent, luminous skin appearance, assists in improving dull and turbid complexion. It serves as a key ingredient for high-end complexion-brightening formulations. 2. Firming Cream & Lotion: Maintains the structural homeostasis of the DEJ basement membrane, helps reduce the visual appearance of superficial fine lines and preserves skin elasticity appearance. 3. Barrier Homeostasis Care & Soothing Stabilizing Cream: Formulation for sensitive skin and soothing care after external irritation; helps improve rough skin texture. 4. Eye Cream / Eye Serum: For conditioning periorbital skin texture and sagging appearance; the raw material is mild in nature. 5. Conditioning Mask: Brightening skincare mask. 6. High-End Primer: Smooths skin texture, improves foundation adherence, and creates natural soft-glow appearance.
Scalp & Hair Care
Scalp texture conditioning and color-protecting hair care products. Relevant literature studies indicate it helps maintain hair pigment homeostasis.
Product FAQ
What is Palmitoyl Tetrapeptide-10?
Palmitoyl Tetrapeptide-10 (INCI: Palmitoyl Tetrapeptide-10, CAS: 887140-79-6) is a synthetic lipophilic signal cosmetic peptide listed in the China Inventory of Existing Cosmetic Ingredients. Its peptide sequence is Palmitoyl-Lys-Thr-Phe-Lys (Pal-KTFK). The palmitoyl fatty chain endows lipophilicity and enhances molecular retention on the skin surface. It targets the dermal-epidermal junction (DEJ) area, regulates the expression of related structural proteins, and maintains homeostasis of DEJ and skin barrier.
What is the recommended dosage of Palmitoyl Tetrapeptide-10? Are there upper and lower limits for the addition concentration?
The recommended dosage is 0.001% ~ 0.05% (calculated as pure peptide). Below 0.001%, in-vitro studies show relatively weak activity; concentrations higher than 0.05% will not significantly boost performance but increase formulation cost.
What is the difference between Palmitoyl Tetrapeptide-10 and Palmitoyl Tetrapeptide-7?
They differ in amino acid sequences and action targets. Palmitoyl Tetrapeptide-10 focuses on DEJ homeostasis regulation and barrier maintenance; Palmitoyl Tetrapeptide-7 mainly modulates inflammatory signals. They can be compounded for synergistic effects but are not interchangeable.
What supply specifications are available for Palmitoyl Tetrapeptide-10?
Standard packages: 1g, 10g, 100g, 1kg. Custom specifications are available upon request.