Palmitoyl Tetrapeptide-20
Palmitoyl Tetrapeptide-20 (commonly known as Hair Darkening Peptide) is a signal peptide cosmetic raw material for hair care. Please indicate your intended use, required purity and purchase quantity when sending inquiries. Xi'an Wanlu welcomes your consultation on this product.
Overview
What is Palmitoyl Tetrapeptide-20?Palmitoyl Tetrapeptide-20, INCI name Palmitoyl Tetrapeptide-20, is a water-soluble signal peptide cosmetic active ingredient modified by palmitoylation. It links a tetrapeptide chain with a palmitoyl fatty acid chain to enhance penetration into the scalp and acts on the follicular microenvironment. In in vitro studies, it exerts antioxidant effects, protects the follicular microenvironment and supports follicular pigment homeostasis via biomimetic signal transduction. It is widely used in cosmetic formulations for scalp care. Disclaimer: The above describes the in vitro mechanistic research of the raw material. It does not mean finished cosmetic products containing this ingredient are capable of reversing grey hair or changing hair color. Efficacy claims for finished products shall be assessed by the filing enterprise in accordance with the Specification for Cosmetic Efficacy Claim Evaluation.
Key Parameters
Applications
Application in Skincare
※ Disclaimer: The following describes in vitro research mechanisms of this raw material, for cosmetic formulation R&D reference only. It does not mean cosmetic finished products containing this raw material can achieve relevant efficacy. Efficacy claims of finished products shall be evaluated by the filing entity in accordance with the Specification for Evaluation of Cosmetic Efficacy Claims. 1. In Vitro Signaling Study: In vitro models show the material can act on the TGF-β signaling pathway and affect the expression of type I and type III collagen. It can be referenced for formulation development targeting early and mature skin aging, compatible with formulation systems such as creams, serums and eye creams. 2. In Vitro Barrier Maintenance Study: In vitro tests demonstrate it can downregulate the release of inflammatory factors including TNF-α and IL-6 and reduce oxidative stress. It can be referenced for formulation development of skin barrier maintenance, compatible with formulation systems such as serums and repair lotions. 3. In Vitro Antioxidation Study: In vitro models indicate it can inhibit protein oxidative denaturation and regulate oxidation-related environments. It can be referenced for antioxidant formulation development, compatible with formulation systems such as serums and repair products.
Application in Hair Care
※ Disclaimer: The following describes in vitro research mechanisms of this raw material, for cosmetic formulation R&D reference only. It does not mean cosmetic finished products containing this raw material can achieve relevant efficacy. Efficacy claims of finished products shall be evaluated by the filing entity in accordance with the Specification for Evaluation of Cosmetic Efficacy Claims. This raw material shall NOT be used for claims such as reversing gray hair, improving gray hair or other hair color-altering effects. 1. In Vitro Hair Follicle Microenvironment Study: In vitro studies show the material can act on follicular melanocytes, affect tyrosinase activity and participate in pathways related to melanin synthesis and transport. It can be referenced for formulation development targeting follicular pigment homeostasis, compatible with formulation systems such as hair tonics, scalp care lotions and scalp treatment serums. 2. In Vitro Scalp Barrier Study: In vitro studies help modulate the scalp microecology and downregulate inflammation-related factors to support scalp and follicle health. It can be referenced for scalp care formulation development, compatible with formulation systems such as scalp serums, hair conditioners and hair masks.
Product FAQ
What is Palmitoyl Tetrapeptide-20?
Palmitoyl Tetrapeptide-20, INCI name: Palmitoyl Tetrapeptide-20, is a water-soluble signaling peptide cosmetic active ingredient modified by palmitoylation. In in vitro studies, it can participate in cellular signal transduction and can be used in the formulation development of skincare and scalp care cosmetics. It is commonly known in the industry as "gray hair peptide", which is only an industry customary name and does not constitute an efficacy claim.
What is the recommended addition rate of Palmitoyl Tetrapeptide-20?
The recommended formulation dosage is 0.001–0.1% (calculated based on peptide content). Performance varies in different formulation systems. Customers are advised to conduct formulation verification prior to mass production.
What are the appearance and solubility properties of Palmitoyl Tetrapeptide-20?
It appears as white powder and is water-soluble, making it easy to incorporate into aqueous formulation systems.
What packaging specifications are available for Palmitoyl Tetrapeptide-20?
Available packages: 1g, 10g, 100g, 1kg, etc. Custom packaging solutions can be negotiated upon request.