Palmitoyl Tripeptide-1Pal-GHK
Palmitoyl Tripeptide-1 (Pal-GHK) is a synthetic lipophilic signaling peptide used as a cosmetic raw material. It is suitable for formulations such as serums, eye creams and facial creams. Full sets of technical documents and samples are available.
Overview
What is Palmitoyl Tripeptide-1?
Palmitoyl Tripeptide-1 (Pal-GHK) is a classic signaling peptide. Its INCI name is Palmitoyl Tripeptide-1, CAS No. 147732-56-7, and it is also the core component of the Matrixyl 3000 system. Modified with a long palmitoyl chain to enhance transmembrane penetration potential. According to literature reports, this peptide can participate in regulating the synthesis of matrix-related proteins in fibroblasts and modulate matrix degradation under in vitro conditions. It is often compounded with Palmitoyl Tetrapeptide-7. The recommended effective dosage in finished cosmetic products is 2~5 ppm. It requires feeding at low temperature and is suitable for cosmetic formulations such as serums and creams. It demonstrates good safety at conventional topical concentrations. Disclaimer: This product is a cosmetic raw material, not a finished skincare product. The content herein only introduces mechanisms from scientific research literature and does not constitute cosmetic efficacy claims. Efficacy claims for downstream finished cosmetic products shall be subject to efficacy evaluation and filing completed by the finished product manufacturer in accordance with relevant regulations.
Learn more ：Palmitoyl Tripeptide‑1｜High-Activity Anti-Ageing Signalling Peptide
Key Parameters
Applications
Cosmetics & Skincare Field
Palmitoyl Tripeptide-1 is a signaling peptide raw material, compatible with various leave-on cosmetic formulations. Core applicable formulations: 1. Serums / Ampoules: Facial serums, stock solutions, single-dose ampoules and other formula systems 2. Eye care products: Eye cream, eye serum formulations 3. Face creams & lotions: Face cream, milk cream formulations 4. Masks: Sheet masks, wash-off mask formulations 5. Other formulations: Neck cream, body lotion, foundation, skincare oils (emulsified system required) Formulation Tip: It is often compounded with Palmitoyl Tetrapeptide-7 to form the Matrixyl 3000 system for cosmetic formula development.
Product FAQ
What is Palmitoyl Tripeptide-1?
Palmitoyl Tripeptide-1 (Pal-GHK) is a classic signaling peptide. Its INCI name is Palmitoyl Tripeptide-1, CAS No. 147732-56-7, and it is the core component of the Matrixyl 3000 system. Modified with a long palmitoyl chain to enhance transmembrane penetration potential. According to literature reports, this peptide can participate in regulating the synthesis of matrix-related proteins in fibroblasts and modulate matrix degradation under in vitro conditions. It is often compounded with Palmitoyl Tetrapeptide-7. The recommended effective dosage in finished cosmetic products is 2~5 ppm. Low-temperature feeding is required. It is suitable for cosmetic formulations such as serums and creams, and shows good safety at conventional topical concentrations.
What is the relationship between Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7?
They form a classic compounding combination. When combined, they constitute the Matrixyl 3000 system. They are frequently used synergistically in formula design as a multi-peptide compounding technical solution.
What is the recommended dosage of Palmitoyl Tripeptide-1?
The recommended effective dosage in finished cosmetic formulations is 2~5 ppm. Higher concentrations do not bring additional benefits. It is recommended to start formula trials at low dosages.
What are the feeding requirements for Palmitoyl Tripeptide-1?
Peptides are sensitive to high temperatures. Low-temperature feeding is mandatory. Avoid prolonged high-temperature heating to prevent peptide degradation. This product has poor water solubility; it can be pre-dissolved in co-solvents such as propylene glycol or ethanol before adding into the formula system.
What packaging specifications are available for Palmitoyl Tripeptide-1?
1g/bottle, 5g/bottle, 10g/bottle, 100g/bottle, 1kg/aluminum foil bag (customization available upon negotiation).