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221227-05-0

Palmitoyl Tetrapeptide-7

Palmitoyl Tetrapeptide-7, off-white powder, CAS 221227-05-0. Xi'an Wanlü supplies COA, MSDS and provides sample support. It is suitable for cosmetic formulations targeting anti-aging firming and soothing repair, and is a supporting peptide component for the Matrixyl 3000 system.

221227-05-0Synthetic lipopeptideDerived from the GQPR tetrapeptide sequence of IgG heavy chain fragment

Overview

What is Palmitoyl Tetrapeptide-7?

Palmitoyl Tetrapeptide-7 (INCI: Palmitoyl Tetrapeptide-7, abbreviated as Pal-GQPR / PT-7, trade name Rigin) is a commonly used synthetic liposoluble polypeptide for cosmetics. It is one component of the Matrixyl 3000 system and is often used together with Palmitoyl Tripeptide-1. It mainly works by inhibiting IL-6 inflammatory factors, reducing the degradation of collagen by metalloproteinases, and promoting the production of fibronectin, laminin and collagen. This mechanism can be applied in firming cosmetic formulations targeting inflammatory aging, fine lines and redness. The suitable pH range for formulation is 5–7, and the recommended active dosage in finished products is 0.0005%~0.005%. It is mild in nature and can be used in anti-aging serums, creams, eye creams and other products, which can be normally filed for domestic cosmetic registration in China.

Key Parameters

Appearance
White to off-white powder
Purity
≥98%
Molecular Formula / Molecular Weight
C₃₄H₆₂N₈O₇ / 694.91
Amino Acid Sequence
Pal-Gly-Gln-Pro-Arg (Pal-GQPR)
Solubility
Slightly soluble in water; soluble in methanol and ethanol. Polyol is required for solubilization in formulations.
Recommended Active Dosage in Finished Products
0.0005% ~ 0.005%

Applications

Cosmetics (Skincare Raw Material)

1. Anti-aging skincare: Applicable to formulations for anti-wrinkle, firming and repairing skincare products targeting early and mature aging skin. 2. Anti-aging for sensitive skin: Suitable for mild anti-aging formulations, ideal for formulating products for skin intolerant to retinol and acids. 3. Periocular care: Can be used in eye cream and eye serum formulations, developed for pathways associated with periocular microinflammation. 4. Skin barrier repair: Applicable to soothing mask and repairing serum formulations, designed for inflammatory aging triggered by external irritants.

Product FAQ

What is Palmitoyl Tetrapeptide-7?

Palmitoyl Tetrapeptide-7 (INCI: Palmitoyl Tetrapeptide-7, abbreviated as Pal-GQPR, CAS: 221227-05-0) is a synthetic lipopeptide, white to off-white powder. It targets and inhibits IL-6 inflammatory factors, reduces MMP metalloproteinases, protects collagen from degradation and promotes dermal matrix protein synthesis. It can be used in anti-inflammatory, anti-aging and soothing & repairing cosmetic formulations, serving as a peptide raw material exclusively for cosmetics.

Is Palmitoyl Tetrapeptide-7 the same as Matrixyl 3000?

No. Palmitoyl Tetrapeptide-7 is a single component. The Matrixyl 3000 system is a complex blend composed of Palmitoyl Tripeptide-1 + Palmitoyl Tetrapeptide-7. Palmitoyl Tripeptide-1 mainly promotes collagen regeneration, while Palmitoyl Tetrapeptide-7 focuses on anti-inflammation and collagen protection. The two ingredients work synergistically when combined.

What is the recommended dosage of Palmitoyl Tetrapeptide-7 in finished products?

The recommended active peptide dosage in finished formulations is 0.0005%–0.005%. If purchasing peptide solution in glycerin / butanediol carrier, calculate the feeding amount based on the labeled active peptide content of the carrier solution.

What are the available packing specifications for Palmitoyl Tetrapeptide-7?

Standard packages: 1g, 10g, 100g, 1kg. Custom specifications are available upon request.