Palmitoyl Pentapeptide-4Pal-KTTKS
Palmitoyl Pentapeptide-4 is a signal cosmetic peptide, widely used for formulation development of firming and repairing skincare products. Please clarify your intended use and quantity before purchase. Xi’an Wanlv can supply relevant products and supporting documents.
Overview
What is Palmitoyl Pentapeptide-4?Palmitoyl Pentapeptide-4, INCI name Palmitoyl Pentapeptide-4, commonly known as Pal-KTTKS, is a classic messenger-type synthetic lipopeptide. The palmitoyl modification improves skin permeability and mimics cutaneous collagen metabolic signals. In vitro cell studies show that it acts on dermal fibroblasts and upregulates the expression of type Ⅰ, Ⅱ, Ⅳ collagens, fibronectin and hyaluronic acid. It is widely used for formulation development targeting skin firming. Mild in nature, it is suitable for cosmetic formulations such as serums, creams and eye creams. The recommended active dosage in finished formulations is 0.001–0.01%, applicable pH range 4.5–7.0. It is often compounded with other peptides for firming-oriented formulation design.
Key Parameters
Applications
Cosmetic & Skincare Applications
Palmitoyl Pentapeptide-4 can be used in leave-on formulations such as serums, eye creams, face creams, facial masks and neck care products. In vitro studies indicate that this peptide has potential to modulate matrix protein expression. It is mild and often combined with other peptide active ingredients. It is suitable for developing skincare formulations for users intolerant to vitamin A ingredients.
Product FAQ
What is Palmitoyl Pentapeptide-4?
Palmitoyl Pentapeptide-4, INCI name Palmitoyl Pentapeptide-4, CAS No. 214047-00-4, commonly known as Pal-KTTKS, is a lipid-modified messenger-type synthetic peptide listed in the List of Used Cosmetic Raw Materials. The palmitoyl modification improves molecular skin permeability. In vitro cell studies show it acts on dermal fibroblasts and modulates the expression of matrix proteins.
What is the recommended dosage and applicable pH range of Palmitoyl Pentapeptide-4?
The recommended active dosage in finished formulations is 0.001–0.01%; applicable pH range is 4.5–7.0. Downstream customers are advised to conduct stability tests according to their own formulation systems.
What are the differences between Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1 and Acetyl Hexapeptide-8?
They differ in mechanism types. Palmitoyl Pentapeptide-4 is a messenger peptide; Acetyl Hexapeptide-8 is a neurotransmitter peptide; Palmitoyl Tripeptide-1 is a signal peptide. They can be used alone or combined based on formulation development goals.
What are the available packaging specifications for Palmitoyl Pentapeptide-4?
Standard packaging: 1 g/bottle, 10 g/bottle, 100 g/bottle, 1 kg aluminum foil bag. Custom packaging solutions are available upon request.