N-Acetylneuraminic acidSialic Acid

Sialic Acid (N-Acetylneuraminic Acid) is a natural water-soluble active raw material, suitable for skin maintenance and conditioning formulas. Please verify application purpose, grade, active content and purchase volume for inquiry. Xi'an Wanlv offers complete documents and sample support.
Overview

What is Sialic Acid (N‑Acetylneuraminic Acid)?Sialic Acid, chemically named N‑Acetylneuraminic Acid (Neu5Ac, CAS: 131-48-6), is a member of the sialic acid family and a naturally occurring carbohydrate derivative. It exists naturally in glycoproteins and glycolipids on the surface of animal cell membranes, and is also the most representative characteristic component in traditional bird’s nest, hence the common name “Sialic Acid (Bird’s Nest Acid)”. Commercially available Sialic Acid raw materials for industrial production are mostly manufactured by microbial fermentation, not extracted from bird’s nest. Powered by biosynthetic technology, high-purity products can be produced stably and on a large scale, breaking the constraints of limited natural bird’s nest output and volatile pricing, with controllable quality and consistent batches. The finished product appears as white crystalline powder. It features excellent water solubility, nearly odorless, good powder flowability and convenient feeding for processing. It also shows favorable compatibility with most food and cosmetic raw materials, suitable for a wide range of formulation systems. From a regulatory perspective, N‑Acetylneuraminic Acid is a novel food ingredient approved by China’s National Health Commission. It can be applied in nutritional foods, solid beverages, pressed candies, oral liquids and other dietary supplement foods. Regulations clearly stipulate that this ingredient shall not be used in infant foods. Meanwhile, N‑Acetylneuraminic Acid can also be used as a cosmetic formulation ingredient, added into serums, facial masks, skin lotions, creams and other cosmetic formulations.
Key Parameters
Applications
Food / Functional Food Sector
Regulatory Basis: National Health Commission Announcement No.7 of 2017. Recommended daily intake ≤500 mg. This ingredient is not applicable to infant foods. Applicable dosage forms: 1. Solid beverages: compound powders, probiotic powders 2. Compressed candies, chewable tablets, soft capsules (dietary supplement forms) 3. Modified milk powder, ready-to-eat bird’s nest, plant drinks, oral liquids 4. Baked goods, nutritional meal replacements and other food systems Formulation Tips: Water-soluble raw material. Late addition is recommended to avoid degradation caused by prolonged high-temperature sterilization. Note: This product is bio-fermented N‑Acetylneuraminic Acid, not extracted from bird’s nest. Only applicable dosage forms are listed; this does not imply the ingredient has health-benefiting effects.
Cosmetic / Skincare Sector
1. Regulatory Information: Listed in Inventory of Existing Cosmetic Ingredients (II). Not recommended for lip products and ingestible cosmetics. 2. Recommended applicable formulations: Serums, facial masks, toners, lotions, creams, eye creams, single-dose preparations, spray formulations. 3. Formulation Features: Water-soluble ingredient, suitable for aqueous systems. Non-photosensitive, compatible for daytime formulations. Remark: This section only describes the formulation characteristics of the raw material and does not indicate skincare efficacy. Finished cosmetic efficacy shall be filed by the finished-product manufacturer in accordance with regulations.
Product FAQ
What is sialic acid and what is its chemical name?
Sialic acid is chemically named N‑Acetylneuraminic Acid (Neu5Ac, CAS: 131-48-6). It belongs to the sialic acid family, a naturally occurring carbohydrate derivative found in organisms. It is also a characteristic component in traditional bird’s nest, hence the common name “bird’s nest acid”. Commercially industrial raw material is produced by microbial fermentation, not extracted from bird’s nest. The finished product is white crystalline powder with good water solubility.
What category of food ingredient is N‑Acetylneuraminic Acid, and what is the regulatory basis?
It is a novel food ingredient approved by China’s National Health Commission (Announcement No.7 of 2017). Recommended daily intake ≤500 mg. Regulations clearly state: not applicable to infant foods. It cannot be used in infant formula powder, complementary foods for infants and young children and other related products.
Can N‑Acetylneuraminic Acid be used in cosmetics? What is its regulatory status?
N‑Acetylneuraminic Acid is listed in the Inventory of Existing Cosmetic Ingredients (II) and can be used as a cosmetic formulation ingredient. It is not recommended for lip products and inhalable cosmetics. Efficacy claims of finished cosmetics shall be filed by the finished product manufacturer.
What packaging specifications are available for sialic acid raw material?
Standard packaging: 1kg / vacuum aluminum foil bag, 25kg / fiber drum. Custom small sample packaging can be negotiated upon customer request. The inner bag is food-grade aluminum foil, light-proof and moisture-proof, suitable for powder storage. The outer package is thickened fiber drum with inner liner bag to provide protection for long-distance transportation.
