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Technical Review2026.09.16

Glutathione: A Comprehensive Review from Raw Material to Application

Reduced glutathione (GSH) is an endogenous core tripeptide active substance in the human body, possessing multiple biological activities such as antioxidation, detoxification, inflammatory response regulation, and melanin metabolism modulation. It is a key component in maintaining cellular redox homeostasis. This article systematically elaborates on the physicochemical properties, core mechanisms of action, and production processes of reduced glutathione, while comprehensively reviewing the application regulations of this raw material in the food and cosmetics fields. It provides theoretical and regulatory support for raw material research and development, formulation implementation, product compliance filing, and market-oriented application.

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Technical Review2026.09.11

Pro-Xylane: A Comprehensive Guide to Mechanism of Action, Comparison with Retinol and Peptides, Regulatory Standards, and Formulation Considerations

In the competitive landscape of anti-aging skincare actives, Pro-Xylane (hydroxypropyl tetrahydropyrantriol) has established itself as a cornerstone ingredient in premium skincare formulations, distinguished by its gentle yet effective profile, compatibility with all skin types, and suitability for long-term use. While most brands highlight its anti-aging and skin-repair benefits, significant questions remain among both consumers and formulation professionals: What exactly is Pro-Xylane? This article offers an in-depth examination across five key dimensions: ingredient definition, mechanism of action, comparative analysis with related actives, domestic and international regulatory frameworks, and formulation contraindications.

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Technical Review2026.09.14

N‑Acetylneuraminic Acid (Sialic Acid) Raw Material Introduction

N‑Acetylneuraminic acid (Neu5Ac, commonly known as bird’s nest sialic acid) is a nine‑carbon amino monosaccharide and an active ingredient applicable for both food and cosmetic use, manufactured via microbial fermentation. In food applications, N‑acetylneuraminic acid participates in nervous system development, maintains mucosal immunity and exhibits antioxidant activity. In cosmetics, it repairs the skin barrier, scavenges free radicals to deliver anti‑aging effects and modulates melanin synthesis. This article reviews the physicochemical properties and mechanism of action of the ingredient, as well as regulatory requirements and applicable product categories for its use in food and cosmetics in China.

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Hydroxyapatite

Technical Review2026.08.19

Hydroxyapatite: The "All-rounder Material" Bridging Biomedicine and Industrial Environmental Sustainability

Hydroxyapatite (also known as hydroxapatite or basic calcium phosphate, with the chemical formula Ca₁₀(PO₄)₆(OH)₂) is a natural mineral biomaterial with extremely high biocompatibility. In its conventional state, it appears as an off-white powder that is insoluble in water, barely soluble in alkali, and readily soluble in acid. As the core inorganic component of human bones and teeth, it has gradually gained a firm foothold in multiple tracks including orthopedic repair, dental care, aesthetic regeneration, and environmental governance by virtue of its unique structural properties, growing into an "all-round player" spanning multiple fields.

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PDRN

2026.08.20

Introduction to Salmon PDRN (Polydeoxyribonucleotide)

Salmon PDRN (Polydeoxyribonucleotide) is a high-purity bioactive substance extracted from the sperm DNA of farmed salmon, consisting of a mixture of linear deoxyribonucleotide polymers with chain lengths ranging from 50 to 2000 base pairs. This ingredient has been widely applied in clinical dermatology, post-procedural wound care, medical aesthetic products, and high-performance functional cosmetics. As a clinically validated active raw material recognized in many countries and regions, its biocompatibility, long-term safety and skin tolerance have been fully verified through decades of clinical practice and experimental research.

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Ceramides

Technical Review2026.08.28

Understanding Ceramides: Sub‑types, Formulation Compounding and Application Directions

Ceramides are core components of intercellular lipids in the stratum corneum. Belonging to the sphingolipid family, they are formed by amide linkage between sphingoid bases and fatty acids, and serve as essential building blocks for lipid bilayers within the stratum corneum. More than ten ceramide subtypes exist in human stratum corneum. Differences in fatty‑acid chain length and hydroxylation patterns enable them to perform distinct roles in the stratum corneum lipid network. In cosmetic formulations, multiple ceramides are frequently combined with other lipids to help sustain the lipid environment of the stratum corneum and alleviate dry skin conditions. This article provides a scientific overview of commonly‑used cosmetic ceramide subtypes, formulation compounding strategies and relevant application directions.

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Ectoine

Technical Article2026.09.02

Differences Between Ectoine, Panthenol and Ceramide: Selection of Repairing Ingredients for Skincare Products

In the formulas of sensitive skin repair, post-procedure soothing and anti-environmental damage skincare products, Ectoine, Panthenol and Ceramide are the three mainstream repairing ingredients. Many formulators and procurement staff often get confused during ingredient selection: what exactly are the differences among the three? Which one delivers stronger repair efficacy, better stability and wider formula compatibility? This article elaborates on the core advantages of Ectoine compared with traditional repairing ingredients from multiple dimensions including ingredient mechanism, experimental performance, formula compatibility and practical effect, so as to provide references for product development.

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Tranexamic Acid

Technical Article2026.09.03

Tranexamic Acid: Properties, Skin Care Mechanism, Differences from Competing Ingredients and Cosmetic Regulatory Requirements

Tranexamic acid (also known as transamin acid) is a water-soluble core whitening and repairing raw material in the beauty industry with high stability and high safety. Relying on its unique anti-inflammatory and melanin-inhibiting mechanism, it can effectively improve problems such as post-inflammatory hyperpigmentation, skin redness and dullness, and is widely applied in scenarios including functional skin care and post-aesthetic medical procedure repair. This article systematically expounds the physicochemical and safety properties as well as the skin care mechanism of cosmetic-grade tranexamic acid. It accurately compares the differentiated advantages between tranexamic acid and the two mainstream whitening raw materials niacinamide and 377 from multiple dimensions covering efficacy, safety, formula mass production and implementation selection. Meanwhile, it sorts out in detail the regulatory requirements for tranexamic acid in China's cosmetic sector, such as the compliant addition concentration, applicable scope and promotion specifications, so as to provide reference for beauty brands in formula R&D, raw material procurement, new product project initiation and compliant production.

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CaHA

Industry Insight2026.08.31

Calcium-Hydroxylapatite (CaHA): A Bioceramic Substrate for Implantable Medical Devices

In the field of biomedical materials, Calcium-Hydroxylapatite (abbreviated as CaHA) is a calcium-phosphate bioactive material that shares high homology with the inorganic components of human bones and teeth. With excellent biocompatibility, it has long been widely applied in clinical scenarios such as orthopedics and stomatology. As China's regulatory system for medical devices continues to improve, the R&D and production of the CaHA-related industry has gradually entered a standardized development stage. This article systematically sorts out dimensions including the basic properties of the material, approved compliant application scenarios, production quality control requirements, and industry compliance guidelines.

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Technical Article2026.09.03

Tranexamic Acid: Properties, Skin Care Mechanism, Differences from Competing Ingredients and Cosmetic Regulatory Requirements

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Featured Stories

Glutathione: A Comprehensive Review from Raw Material to Application

Pro-Xylane: A Comprehensive Guide to Mechanism of Action, Comparison with Retinol and Peptides, Regulatory Standards, and Formulation Considerations

N‑Acetylneuraminic Acid (Sialic Acid) Raw Material Introduction

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Hydroxyapatite: The "All-rounder Material" Bridging Biomedicine and Industrial Environmental Sustainability

Introduction to Salmon PDRN (Polydeoxyribonucleotide)

Understanding Ceramides: Sub‑types, Formulation Compounding and Application Directions

Differences Between Ectoine, Panthenol and Ceramide: Selection of Repairing Ingredients for Skincare Products

Tranexamic Acid: Properties, Skin Care Mechanism, Differences from Competing Ingredients and Cosmetic Regulatory Requirements

Calcium-Hydroxylapatite (CaHA): A Bioceramic Substrate for Implantable Medical Devices

All Articles

No stories in this category yet

Hydroxyapatite: The "All-rounder Material" Bridging Biomedicine and Industrial Environmental Sustainability

Introduction to Salmon PDRN (Polydeoxyribonucleotide)

Understanding Ceramides: Sub‑types, Formulation Compounding and Application Directions

Differences Between Ectoine, Panthenol and Ceramide: Selection of Repairing Ingredients for Skincare Products

Tranexamic Acid: Properties, Skin Care Mechanism, Differences from Competing Ingredients and Cosmetic Regulatory Requirements

Calcium-Hydroxylapatite (CaHA): A Bioceramic Substrate for Implantable Medical Devices